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Home Non-Invasive Blood Pressure Panlab Non-Invasive Blood Pressure System for Rodents and Dogs


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Panlab Non-Invasive Blood Pressure System for Rodents and Dogs

Panlab Harvard Apparatus NIPB system provides an easy and reliable technique to measure systemic blood pressure and cardiovascular parameters in rodents without any invasive catheterization.

The pulse signal level (heart rate) is permanently monitored on the LCD display while an internal pressure transducer is constantly measuring the current pressure applied on the cuff. Measurement process involves several steps which are performed automatically; systolic and diastolic blood pressure and calculated mean blood pressure are visualized in real time on the digital display of the control unit. With regards to the systolic pressure, it can be achieved either once the heart pulse disappears or when the first pulse reappears (user selectable) after the occlusion process.

Single and Multiple Animals Systems are available. The Multiple Animal Systems allows a sequential measurement of 6 to 12 animals without having to change the pulse transducers and tails cuffs.

Search for Product in current catalog
Item Listing Full Description Specifications Journal Articles Manuals
Item# Description
760012 Pulse Transducer and Cuff for Mice and Rats up to 150 g, Model LE5160M
760013 Pulse Transducer and Cuff for Rats, Model LE5160R
760014 Pulse Transducer for Dogs (18 mm diameter), no cuff, Model LE5015
760015 Pressure Cuff for Dogs, Model LE5012
760173 Basic Unit for Panlab N.I.B.P., Model LE5001
760174 Standard Unit for Panlab N.I.B.P. with Memory and R-S232 Serial Port, includes SeDaCom software, Model LE5002
760175 Complete Unit for Panlab N.I.B.P. with Scheduled Data Acquisition (up to 12 animals), Memory and RS-232 Serial Port, includes SeDaCom Software, Model LE5007
760177 Electronic Rat Simulator, Model LE5090
760178 Heater for Single Animal, Model LE5610
760179 Automatic Heater and Scanner for six rats or six mice, Model LE56506
760180 Automatic Heater and Scanner for six mice, Model LE56606
760183 Mice Holder, Small (15 to 25 g), Model LE5016
760184 Mice Holder, Large (25 to 40 g), Model LE5018
760185 Rat holder (150 g),Model LE5020
760186 Rat holder (250 g), Model LE5022
760187 Rat holder (400 g), Model LE5024
760188 Rat holder (500 g), Model LE5025
760432 Pulse Transducer and Cuff for Mice, Model LE5160MM
760466 NIBP System Software for the traceability and graphical validation of the data supplied by the LE5001, LE5002 or LE5007

For local pricing, contact your nearest distributor.



Full Description Back to Top

Features:
• Total reliability to realize consecutive measurements on the same animal
• Analogic signal output for recording cuff pressure and pulse signals in a PC
• Automated deflation driven separately for each animal (minimize tail lesions)
• Automated cuff inflation/deflation at a very constant rate
• The same system can be used for rat/dog/mice
• Real values provided (without any linear regression calculation)
• Easily traceable data (using a data acquisition software)
• Parameters evaluated can be visualized on-line on the digital display

Panlab Harvard Apparatus NIPB system provides an easy and reliable technique to measure systemic blood pressure and cardiovascular parameters in rodents without any invasive catheterization.

The pulse signal level (heart rate) is permanently monitored on the LCD display while an internal pressure transducer is constantly measuring the current pressure applied on the cuff. Measurement process involves several steps which are performed automatically; systolic and diastolic blood pressure and calculated mean blood pressure are visualized in real time on the digital display of the control unit. With regards to the systolic pressure, it can be achieved either once the heart pulse disappears or when the first pulse reappears (user selectable) after the occlusion process.

Single and Multiple Animals Systems are available. The Multiple Animal Systems allows a sequential measurement of 6 to 12 animals without having to change the pulse transducers and tails cuffs. A built-in air pump ensures automated cuff inflation/deflation at a constant and even rate. In order to avoid deterioration of the animal?s tail after submitting animals to unnecessary high occlusion pressures, the automated deflation is carried out for each animal and separately, once their own systolic value is reached. Real values (without linear regression calculation) are thus achieved while remaining easily traceable: visualization of the signal through data acquisition software NIBPChart. All units can be used for rats, mice or dogs, using specific pulse transducers and cuffs. All accessories are supplied separately. Once you've chosen the control unit, you will need to choose the appropriate transducer/cuff and animal holder (restrainer). These accessories need to be ordered separately. Restrainers are not required for anesthetized animals. An electronic simulator, heater and scanner are also available if needed.

The requirement of a warm environment for the animals is critical for accurate blood pressure measurements. To provide adequate conditions for NIBP measurement, the system can be used with a warming chamber which provides a comfortable and heated environment necessary to produce peripheral vasodilatation and isolate the animal from external noise.

Parameters Measured
• Systolic blood pressure
• Diastolic blood pressure
• Mean blood pressure
• Heart rate

Components included
• Control Unit with RS-232 serial port (except LE 5001)
• SeDaCom software (except LE 5001)
• Instructions manual
• Cables, connectors
• Set of two spare fuses
• 2 year warranty

Options
• PC interface and USB connection for monitoring of pressure and pulse wave signals. Chart™ software included simple or multiple animals heating units

Citations
Ambuhl PA et al. (2007) A vaccine for hypertension based on virus-like particles: preclinical efficacy and phase I safety and immunogenicity. J. Hypertencion. 25(1): 63-72. (mouse, rat, Switzerland)
Amadeu TP et al. (2007) S-nitrosoglutathione-containing hydrogel accelerates rat cutaneous wound repair. J. Eur. Aca. Dermatol. Venereol. 21(5): 629. (LE5001, rat, Brazil)
Moreira-Rodrigues M et al. (2007) Renal Dopaminergic System Activity in Uninephrectomized Rats up to 26 Weeks after Surgery. Am. J. Nephrol. 27(3): 232-239. (rat, Portugal)
Potenza MA et al. (2007) Epigallocatechin Gallate, a Green Tea polyphenol, improves endothelial function and insulin sensitivity, reduces blood pressure, and protects against myocardial ischemia/reperfusion injury in spontaneously hypertensive rats (SHR). Am. J. Physiol. Endocrinol Metab. In process. (LE5001, rat, Italy, USA)
Trevenzoli IH et al. (2007) Neonatal hyperleptinaemia programmes adrenal medullary function in adult rats: effects on cardiovascular parameters. J. Physiol. 580(2): 629. (rat, Brazil)


Specifications Back to Top

Specifications760012760013760014760015760173760174760175760177760178760179760180760183760184760185760186760187760188760432760466
ModelLE5160MLE5160RLE5015LE5012LE5001LE5002LE5007LE5090LE5610LE56506LE56606LE5016LE5018LE5020LE5022LE5024LE5025LE5160MMNIBPCHART
Certifications    CECECE            
Dimensions W x D x H    360 x 340 x 120 mm60 x 340 x 170 mm60 x 340 x 170 mm            
Computer Requirements only if SeDaCom is used     PC (Windows 95, 98, ME, NT, 2000 or XP)PC (Windows 95, 98, ME, NT, 2000 or XP)PC (Windows 95, 98, ME, NT, 2000 or XP)            
Power Supply    110V/220V, 50/60Hz110V/220V, 50/60Hz110V/220V, 50/60Hz            

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Journal Articles Back to Top

Displaying 1 to 10 of 13results for Panlab Non-Invasive Blood Pressure System for Rodents and Dogs   Page 1  2 

Score

Document

Description

100% Login to view PDF10006.pdf
[415 KB]
Non-invasive magnetic resonance imaging assessment
100% Login to view BP04 bsc 23.pdf
[415 KB]
Non-invasive magnetic resonance imaging assessment
44% Login to view HS08 pressure transducer.pdf
[46 KB]
Pressure Transducer use in finding blood pressure and heart rate spectral changes
20% Login to view HS15 Myoglobin facilitates oxygen diffusion.pdf
[631 KB]
Isolated Heart Apparatus use in Myoglobin facilitating oxygen diffusion
17% Login to view PP56 Pump.pdf
[138 KB]
Reduced NO enhances the central gain of cardiac sympathetic afferent reflex in dogs with heart failure
17% Login to view PP50 Blood Pump Model 1421.pdf
[141 KB]
Analysis of Slipstream Flow in a Wide-necked Basilar Artery Aneurysm with use of Blood Pump
13% Login to view PP94 Aquaporin Deletion in Mice Reduces Intraocular Pressure and Aqueous Fluid Production.pdf
[722 KB]
Aquaporin Deletion in Mice Reduces Intraocular Pressure and Aqueous Fluid Production
13% Login to view VT31 Sickle RBC's and NOS Inhibition decrease rat cerebral blood flow.pdf
[515 KB]
Sickle RBC's and NOS Inhibition decrease rat cerebral blood flow
12% Login to view VT06 Ventilator use in finding load as an acute determinant of end-diastolic pressure-volume relation.pdf
[200 KB]
h4Ventilator use in finding load as an acute determinant of end-diastolic pressure-volume relation010100051p
11% Login to view VT25 Ventilator.pdf
[147 KB]
MiniVent use in finding Evidence for Synergy Between Adrenergic and Nonadrenergic Mechanisms in Central Blood Pressure Regulation
   

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Manuals Back to Top

Displaying 1 to 5 of 5results for Panlab Non-Invasive Blood Pressure System for Rodents and Dogs  

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Document

Description

100% Login to view metric system trivia.pdf
[146 KB]
Microsoft Word - Lesson1.doc
99% Login to view 603002 603003.pdf
[77 KB]
Research Grade Blood Pressure Transducer Manual
90% Login to view 724488 724489.pdf
[124 KB]
Research Grade Blood Pressure Transducer Manual
71% Login to view IH-SR Brochure.pdf
[7 MB]
Isolated Heart Perfusion System for Small Rodents IHSR IH-SR
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[139 KB]
Series 1400 Pulsatile Blood Pumps Manual
   

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