Welcome to Harvard Apparatus Limited! Login / Register
Search

Search for these keywords
Home Catalogs Online Technical Resources My Account
Advanced Search   
Products by Category

Featured Products
Warner Cell Electrophysiology & Cell Biology Research
Hugo Sachs Elektronic Isolated Organ and Tissue Systems
BTX Electroporation and Electrofusion Products
Panlab Behavior Research Products
Hoefer Electrophoresis Products
Coulbourn Instruments
Clark Glass Products
Navicyte Ussing/Diffusion Chambers
CMA
Harvard Apparatus
 

Home Behavior Research Products Analgesia Meters Tail Flick Analgesia Meters


Larger Views

 

Tail Flick Analgesia Meters

This system features radiant heat applied on the animal's tail; when the animal feels discomfort, it reacts by a sudden tail's movement (tail flick) which automatically stops the stimulation and the timer for the measurement of the animal reaction time (period from the beginning of the stimulation until detection of the animal's response).
Search for Product in current catalog
Item Listing Full Description Specifications Manuals
Item# Description
760293 Tail Flick Analgesia Meter Including SeDaCom Software

For local pricing, contact your nearest distributor.



Full Description Back to Top

• Optimal detection due to perfect alignment of heat stimulus and photo beam trigger
• Photo beams with adjustable sensitivity
• A light beam shows the point on which the heat source will focus
• Manual and remote timer
• Groove for correct tail placement
• Automatic cut-off
• Computer interface

This system features radiant heat applied on the animal's tail; when the animal feels discomfort, it reacts by a sudden tail's movement (tail flick) which automatically stops the stimulation and the timer for the measurement of the animal reaction time (period from the beginning of the stimulation until detection of the animal's response).

This test has proved particularly sensitive for studying the analgesic properties of pharmacological substances. It can also be used to evaluate basal thermal pain sensitivity or to study putative genetic differences among animals without drug ('naïve').

The LE7106 Tail-flick Meter consists of a Stimulation Unit (containing the halogen lamp for the heat stimulus) and an electronic Control Unit. The system can be used for rats and mice of different sizes. The animals are placed with its tail protruding within a restraining tube on the platform of the Stimulus Unit. The animal's tail is positioned on a slot of adjustable width equipped with a groove that guarantees a correct placement. A remote foot-switch controls the test start/stop allowing rapid hands-free experiments.

A photo beam with adjustable sensitivity detects the tail flick and the latency is automatically presented on a digital display on the Control Unit. Measurements of reaction time are given with a 0.1 precision. A cut-off time can be set to avoid tissue damage (by default: 20 s). The groove system for the tail and the adjustment of response sensitivity ensure optimum repeatability and reliability of results.

SeDacom software supplied with the unit can be used to automatically record the results on a PC through a RS-232 port.

Citations
Andriambeloson E et al. (2006) Interleukin-6 attenuates the development of experimental diabetes-related neuropathy. Neuropathology. 26(1): 32-42. (rat, France)
Cendán CM et al. (2005) Antinociceptive effects of haloperidol and its metabolites in the formalin test in mice. Psychopharmacol. 182(4): 485-493. (mouse. Spain)
Grillet N et al. (2005) Generation and characterization of Rgs4 mutant mice. Mol. Cell. Biol. 25(10): 4221-4228. (mouse, France)
Moncada A et al. (2005) Inhibitors of serine/threonine protein phosphatases antagonize the antinociception induced by agonists of alpha 2 adrenoceptors and GABAB but not kappa-opioid receptors in the tail flick test in mice. Pain 114(1-2): 212-220. (mouse, Spain)


Specifications Back to Top

Specifications760293
Model NumberLE7106
Computer RequirementsWindows 95, 98, ME, NT, 2000, and XP
Catalog PagesG24
Material CompositionMethacrylate, halogen lamp
Maximum Number of Stations1 per computer (multiple setups available by request)
Power Requirements110V/220V, 50/60Hz
CertificationCE
SeDaCom IncludedYes
Control Unit Width350 mm
Control Unit Depth350 mm
Control Unit Height130 mm
Stimulation Unit Width400 mm
Simulation Unit Depth140 mm
Stimulation Unit Height155 mm

Back to Top



Manuals Back to Top

Displaying 1 to 1 of 1result for Tail Flick Analgesia Meters  

Score

Document

Description

100% Login to view tail flick manual.pdf
[136 KB]
Tail Flick Analgesia Meter Manual
   

Back to Top

Breakthrough Products for Regenerative Medicine
2011 Regenerative Medicine Brochure
100's of Innovative products developed with leading scientists & surgeons!
  • Injection & Perfusion
  • Bioreactors
  • Biosensing
  • Total Solutions
  • Total Support


Announcing the new
PHD ULTRA™ Syringe Pumps

Click here for more information about PHD ULTRA™ Syringe Pumps and to download a brochure.

  • Patent pending mechanical design provides highest accuracy/precision & smoothest flow
  • Easy operation with advanced touch screen
  • Advanced EZ PRO™ software for PC functions without a PC.


Sign-up for a FREE Full Line Bioresearch Catalog
CLICK HERE!

  • Over 11,000 specialty products to enhance your bioresearch
  • Enhanced solutions for small animal research
  • 100's of pages of specialized information on instrumentation, applications, uses of products

 

Products on this website are for Research Use Only. Not for use in humans unless
proper investigational device regulations have been followed.


Privacy Policy   |   Terms and Conditions   
Copyright© Harvard Apparatus Ltd. - All rights reserved.
(44) 1732-864001
Website-related comments or concerns can be emailed to our webmaster.

Anesthesia Equipment Animal Handling Products Behavior Research Products Biological Measurement Products Cardiovascular Products Cell Biology Products Microincubation / Microinjectors CPK® Atomic Models Delivery & Sampling Products Dialysis / Sample Prep / SPE Electroporation / Transfection Electrophysiology Products General Laboratory Products Homeothermic/Temperature Control Isolated Organ & Isolated Tissue Molecular Biology Products Neuroscience Products Non-Invasive Blood Pressure Physiology Products Respiratory Products Stereotaxic Instruments Surgical Equipment Surgical Instruments Syringe Pumps/Peristaltic Pumps Tubing & Connectors Ventilators