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• Turnkey system for perfusing isolated organs in-situ or ex-vivo
• Ideal for perfusing isolated organs such as:
– Liver – Heart
– Kidney – Mesenteric bed
– Rabbit Ear – Rat hind limb
• Perfusion can be performed at constant pressure or constant flow without involving any modification of apparatus
• Ideal replacement for perfusion system with hydrostatic pressure generation, low perfusate volume in use, perfusion pressure up to 300 mmHg possible
• Can be equipped with oxygenator for optimal aeration of perfusate containing albumin or erythrocytes
The UP-100 is a multi purpose perfusion system best utilized when different types of organs must be perfused either in situ or ex vivo. The modular design of this system allows easy adaptation to different applications using additions or extensions to the base unit.
Applications for in situ perfusion of hind limb, hindquarter mesenteric bed, liver, kidney:
• Blood vessel tone in peripheral vascular bed
• Balance tests by muscle work (glucose / lactate / pyruvate, high energy phosphates / orthophosphate, etc.)
• Test of vasodilative drugs in occlusive diseases of legs
• Test of muscle relaxants (end-plate pharmacology)
Applications for ex-vivo perfusion using a moist chamber of liver, kidney, mesenteric bed:
• Test of vasodilative drugs
• Studying metabolic processes
• Neural vascular tone
• Organ preservation for transplant
Applications for perfusion of isolated mouse, rat, guinea-pig or very small rabbit heart
Perfusion according to Langendorff. Constant flow or constant pressure perfusion are available using the same equipment.
• If isolated heart is only used occasionally and basic parameters are needed
• For student lab
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