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tissue bath systems
9
Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com
M Series Myograph System
For Force Measurements in Very Small Tissues
advanced
research
Features and Benefits:
Precision Fabrication permits use of tissue
samples with lumen diameters down to
60m and segment lengths up to 3 mm
True Isometric Measurement: rigidly mounted
transducer exhibits less than 12.5 m deflection
at 0.5gm force
Transducer Safety Lock to protect the integrated
force transducer during the preparation phase
Lighted Chamber to assist in tissue mounting
Sliding Wrist Rest for easy manipulation of the
chambers during use
Ideal 5ml working volume sample chamber
Integrated Temperature Controller for optimal
physiological maintenance
Available as the M4 four channel and M1 single
channel Myograph system configurations.
Complete Myography workstation ready for
interface to any Harvard Apparatus Data Acquisi-
tion System
The New M Series Myograph is designed for researchers performing
contractile force studies on small ring samples with sizes ranging from
60m to over 1 mm diameter. That includes mouse aortic rings and small
intestinal ring samples down to micro-vessel preparations, such as
mesenteric arteries.
Order # Product
72-9434 Radnoti M4 4-Channel Myograph System, 115VAC
72-9435 Radnoti M1 1-Channel Myograph System, 115VAC
72-9436 Radnoti M4 4-Channel Myograph System, 220VAC
72-9437 Radnoti M1 1-Channel Myograph System, 220VAC
72-9438 Peristaltic Pump Quad Bank
72-9430 Replacement Wire for Myograph, 25 micron, pack of 10
72-9431 Replacement Wire for Myograph, 50 micron, pack of 10
72-9432 Replacement Wire for Myograph, 75 micron, pack of 10
72-9433 Replacement Wire for Myograph, 125 micron, pack of 10
Using precision fabricated micro vessel support brackets, the system
accommodates lumen diameters down to 60m and segment lengths up to
3mm. To mount the vessel segment, two individual parallel wires are
passed through the sample lumen and attached to the micro vessel
support brackets. Each vessel support bracket incorporates a micro
groove on the face to aid in maintaining the wire position when mounting.
One bracket is connected to a precision 0-0.5 gm capacitance type
isometric force transducer (switchable to 0-5 gm and also available in
0-2 gm/0-20 gm configurations) that provides a true isometric
measurement, i.e. less than 12.5 m deflection at 0.5 gm force, which is
critical when working with small vessel samples. The opposing support
bracket is connected to a precision micrometer controlling the X axis
movement, with Y and minor Z axis positioning controls conveniently
positioned on the Myograph chamber, allowing for precise alignment of
the micro vessel support brackets. The wires are then anchored via a
locking screw on each of the brackets. The locking screws feature a small
bushing that is incorporated under the screw head greatly improving
capture of the support wire. A pre-load tension is then applied via
adjustment of the X axis micrometer.