background image
i
s
o
l
a
t
e
d

h
e
a
r
t

s
y
s
t
e
m
s
I
s
o
l
a
t
e
d

O
r
g
a
n

&

T
i
s
s
u
e
isolated heart systems
31
Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com
IH-SR Isolated Heart for Small Rodents
Mouse, Rat and Guinea Pig (continued)
System Description
The apparatus by design is constructed to be very compact, improved for
low volume and high temperature stability.
All of the components are mounted on a basic Plexiglas stand except for the
thermostatic circulator and the measuring instruments. Special attention has
been made to ensure constant and defined temperature conditions in the heart.
All critical parts in this respect are arranged inside the unique temperature
stable heart chamber, thus avoiding any cooling through a temperature gradient
to ambient temperature.
The key part of the system is the unique aortic block. A clever arrangement
of balls around the aortic cannula allows to mount easily by means of the
miniature ball joint holders all the available measurement electrodes (ECG,
MAP, electrical stimulation...) and collecting cannulae. This system can be
upgraded from a simple Langendorff system to Working Heart and for many
specific applications. The modular setup allows a continuously evoluting
system. Many customized version are also available.
The connection to the heart is made through interchangeable aortic cannulae
and atrial cannulae in working heart extension. The perfusate is aerated by
bubbling in the reservoir. When the perfusate contains erhytrocytes or albumine,
a special membrane oxygenator to prevent foaming can equip the unit.
To get started, select the basic system then add specific options to suit the
particular needs of your study. If any questions arise, our expert technical team
of scientists and engineers is always ready to assist with system configuration,
application support or custom design requests.
Order # Product
Langendorff System & Options
73-4018 Basic IH-SR (Core System requires
option 73-4019 or 73-4020)
73-4019 Additions to IH-SR core system for Mouse hearts
73-4020 Additions to IH-SR core system for Rat hearts
73-4021 Direct Flow Measurement for Mouse Hearts
73-4022 Direct Flow Measurement for Rat Hearts
73-4023 Measurement of ECG Lead II
73-4024 Pacing
73-4025 Measurement of One Epicardial
Monophasic Action Potential on Mouse Hearts
73-4026 Measurement of One Epicardial
Monophasic Action Potential on Rat Hearts
73-4027 Measurement of Endocardial
Monophasic Action Potential on Rat Hearts
73-4028 Cannulating System for Pulmonary Artery
on Rat Hearts for Metabolic Studies
73-4029 pO
2
Measurement
73-4030 pH Measurement
73-4031 pCO
2
Measurement
Additions to the Core System for a Working Heart
73-4032 Working Heart Option (requires 73-4033 or 73-4034)
73-4033 Addition to WH-Option for Mouse Hearts
73-4034 Addition to WH-Option for Rat Hearts
73-4035 Measurement of Cardiac Output for Mouse Hearts
73-4036 Measurement of Cardiac Output for Rat Hearts
73-4037 LVP Measurement in Mouse Hearts
73-4038 LVP Measurement in Rat Hearts
73-4043 Pressure-Volume Loop Measurement in Mouse Hearts
73-4044 Pressure-Volume Loop Measurement in Rat Hearts
Data Acquisition Options
73-4039 Data Acquisition and Evaluation System ISOHEART
73-4040 Data Acquisition and Evaluation System PowerLab
Drug Application Options
73-4041 Drug Application
73-4042 Drug Application Flow Controlled in Constant
Pressure Mode
Other Additions or Options
73-4045 Additions for Cardioplegia Solution Application
73-2481 Low-Temperature Thermociculator, 230V
73-2981 Low-Temperature Thermociculator, 115VAC
73-4046 Cell Isolation with IH-SR Basic System
73-4047 Temperature Measurement
73-4048 Oxygenating System for Foaming
Solutions Containing Albumin or Fatty Acids
73-3329 Effluate Fraction Collection
73-4049 Multi-Mapping ECG, 32 Microelectrodes
73-4050 Multi-Mapping ECG, 64 Microelectrodes
advanced
research
Contact us to receive
the
NEW
detailed IH-SR
Isolated Heart System
brochure. Please visit our
website or call us to request
your FREE copy today!