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Home Behavior Research Products Tail Suspension Test


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Tail Suspension Test

The automatic tail-suspension test allows a fast and reliable screening of the psychotropic properties (anti-depressants, sedatives) of drugs.
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Item Listing Full Description Specifications Manuals
Item# Description
760490 Tail Suspension Test Chambers - Set of 3 Boxes Including Transducers and Electronic Elements
760492 Software and Interface for Tail Suspension Test

For local pricing, contact your nearest distributor.



Full Description Back to Top

• Fast evaluation of antidepressive, psychotropic drugs
• Up to 6 mice at the same time
• Automatic measurement of immobility of suspended mouse
• Capable of automatic randomization
• Reanalysis enhanced, immobility threshold can be readjusted
• Direct exportation of the results into Excel®
• Calculates energy and power in motion

The automatic tail-suspension test allows a fast and reliable screening of the psychotropic properties (anti-depressants, sedatives) of drugs.

Basically, the measuring principle is based on the energy developed by mice trying to escape from their suspension. During the test, the movements of the mice are analyzed in terms of force, energy and power developed over time.

The system includes the suspension cages (3 mice per cage) and a user-friendly software to run, record, analyze and replay the experiments. The results are either printed or stored in .txt or.xls files formats.

Citations
Alexandre C et al. (2006) Early Life Blockade of 5-Hydroxytryptamine 1A Receptors Normalizes Sleep and Depression-Like Behavior in Adult Knock-Out Mice Lacking the Serotonin Transporter. J. Neurosci. 26(20): 5554-5564. (mouse, France, Germany)
Cryan J et al. (2004) The tail suspension test as a model for assessing antidepressant activity: review of pharmacological and genetic studies in mice. Neurosci. Biobehav. Rev. 29(4-5):571-625. (mouse, Switzerland)
Mombereau C et al. (2004) Genetic and Pharmacological Evidence of a Role for GABAB Receptors in the Modulation of Anxiety- and Antidepressant-Like Behavior. Neuropsychopharmacol. 29:1050-1062 (mouse, Stwitzerland)
Strekalova T et al. (2004) Stress-Induced Anhedonia in Mice is Associated with Deficits in Forced Swimming and Exploration. Neuropsychopharmacol., 29(11):2007-17 (mouse, Germany).


Specifications Back to Top

Specifications760490760492
Model NumberBSTST2CABSTST2LOG
Computer RequirementsWindows XP, One free PCI Slot RequiredWindows XP, One free PCI Slot Required
Catalog PagesG57G57
Material CompositionBlack and White Perspex, metal hook 
Maximum Number of Stations6 Stations Per Computer 
Power Requirements110/220V, 50/60 Hz 

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Manuals Back to Top

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Document

Description

100% Login to view tail flick manual.pdf
[136 KB]
Tail Flick Analgesia Meter Manual
   

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