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Home Behavior Research Products Analgesia Meters Incapacitance Meter


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Incapacitance Meter

The Incapacitance test represents an unsurpassed method for assessing spontaneous pain in laboratory animal model with inflammation or nerve injury in one hind paw (neuropathy, carrageenin, incision╔). Indeed, classic measurements of nociceptive thresholds as used in most of the experimental studies allows assessment of only a pain sensitivity level, not a spontaneous pain level, in the absence of experimental nociceptive stimuli.
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Item# Description
760115 Incapacitance Test Sensor
760116 Incapacitance Test Holder, Mouse
760117 Incapacitance Test Holder, Rat
760118 Incapacitance Test Control Unit, SeDaCom Software Optional

For local pricing, contact your nearest distributor.



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• Assess spontaneous pain in absence of the application any experimental noxious or non-noxious stimulus
• Specially designed animal holders (mouse and rat) to get relevant results more rapidly
• Data given using user selected unit (grams, Newton, oz./lbs.) • Easy and precise instrument

The Incapacitance test represents an unsurpassed method for assessing spontaneous pain in laboratory animal model with inflammation or nerve injury in one hind paw (neuropathy, carrageenin, incision╔). Indeed, classic measurements of nociceptive thresholds as used in most of the experimental studies allows assessment of only a pain sensitivity level, not a spontaneous pain level, in the absence of experimental nociceptive stimuli.

In the incapacitance test, the animal is located in a holder specially designed to maintain the animal comfortably positioned on two separated sensor plates. The Panlab/Harvard Apparatus Incapacitance tester enables then to quantify the spontaneous postural changes reflecting spontaneous pain by independently measuring the weight that the animal applies each hind paw on two separate sensors. In the absence of hind paw injury, rats applied equal weight on both hind paws, indicating a postural equilibrium. After unilateral hind paw tissue injury, a change in the weight distribution on the sensor can be detected, with a lower weight applied by the injured paw.

The current value of the weight applied on each sensor is shown on the LCD display of the LE7950 control unit in a user-selected unit (grams, Newton or oz/lbs). A remote foot-switch controls the test start/stop allowing rapid hands-free experiments. The control unit also allows to compute and display statistics (mean, SD) for the groups of animals under test during the measurements. No PC is required for running the incapacitance test, although the possibility is given to send collected data from the instrument to a PC through the integrated RS-232 interface SeDaCom.



Specifications Back to Top

Specifications760115760116760117760118
Model NumberLE7900LE7920LE7930LE7950
Catalog PagesG35G35G35G35
SeDaCom IncludedYesYesYesYes
Resolution0.05 grRS-232 (USB)RS-232 (USB)17 cm
Average1 to 300 secMiceRats (up to 500 gr)25 cm
Overpressure2000 gr  10 cm
CommunicationsRS-232 (USB)  RS-232 (USB)
Animal SuitabilityMice and Rats (up to 500 gr)  Mice and Rats (up to 500 gr)
Control Unit Width    
Control Unit Depth    
Control Unit Height    

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Manuals Back to Top

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100% Login to view tail flick manual.pdf
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Tail Flick Analgesia Meter Manual
   

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