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Home Isolated Organ & Isolated Tissue HSE Tissue Superfusion Systems Coleman Superfusion Bath System


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Coleman Superfusion Bath System

In the Coleman Superfusion Bath, the tissue is located in a horizontally split chamber. The lower part of the chamber can be swung away to simplify access to the preparation. The lower end of the tissue is held by a stainless steel hook. The thread attached to the top of the tissue passes through an opening at the top of the chamber for direct connection to the force transducer. The superfusion solution is fed by a multi-channel roller pump through a stainless steel cannula to the thread and it runs down the thread and superfuses the tissue. Two separate solution paths are available for superfusion with and without test substance. Two platinum wires for field stimulation are placed parallel to the tissue to form the stimulation field. The solution running down provides electrical contact between the electrodes and the tissue. The superfusion vessels are made from an acrylate block and do not require thermostating owing to the low thermal conductivity of the material used.
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Item# Description
739922 Coleman Superfusion Tissue Bath System

For local pricing, contact your nearest distributor.



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• Applications:
– Evaluation of the potency of labile substances
– Determining the rates of onset and offset of drug action
– Evaluation of spasmogenic and spasmolitic agents
• Compact, allows the study of up to four tissue preparations in parallel
• Rapid removal of potentially toxic metabolites
• Obviates the necessity of repeated washing procedures
• Rates of onset and offset of drug action are easily measured

In the Coleman Superfusion Bath, the tissue is located in a horizontally split chamber. The lower part of the chamber can be swung away to simplify access to the preparation. The lower end of the tissue is held by a stainless steel hook. The thread attached to the top of the tissue passes through an opening at the top of the chamber for direct connection to the force transducer. The superfusion solution is fed by a multi-channel roller pump through a stainless steel cannula to the thread and it runs down the thread and superfuses the tissue. Two separate solution paths are available for superfusion with and without test substance. Two platinum wires for field stimulation are placed parallel to the tissue to form the stimulation field. The solution running down provides electrical contact between the electrodes and the tissue. The superfusion vessels are made from an acrylate block and do not require thermostating owing to the low thermal conductivity of the material used.
The superfusion chambers are mounted on a horizontal support rod according to the number of channels required. A stand for 4-position superfusion system is available. The superfusate is thermostated immediately before entering the chamber by a two line heat exchanger supplied from a water thermostat. The heat exchanger is made of a tubing coil that can be easily replaced. A collecting trough is located underneath the superfusion chambers for collecting of the used solution; alternatively the superfusate can be collected from the chamber outlet for recirculation.


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Displaying 1 to 10 of 22results for Coleman Superfusion Bath System   Page 1  2  3 

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Description

100% Login to view HS03F3 Potassium channal inhibition in coronary arteries.pdf
[536 KB]
Force Displacemen Transducer, 5-hydroxytryptamine is a mediator of 4-aminopyridine induced contractions in porcine and human isolated coronary arteries
98% Login to view HS19 Organ Bath.pdf
[259 KB]
Organ Bath use in Aging and Chronic Hypertension Decrease Expression of Rat Aortic Soluble Guanylyl Cyclase
83% Login to view HS02IS Evaluation of Skeletonized LITA.pdf
[228 KB]
Isolated Organ Set use in Intraoperative and Laboratory Evaluation of Skeletonized Versus Pedicled Internal Thoracic Artery
83% Login to view HS19 Soluble Guanylyl Cyclase in Aging and Hypertension.pdf
[238 KB]
hy010000043p
83% Login to view HS01 Opioids and Coronary Vascular Tone.pdf
[138 KB]
Force Transducer influence of opioids on the vascular tone of isolated porcine coronary artery segments
77% Login to view OT31.pdf
[673 KB]
Development of a multiplexed microbioreactor system for high throughput bioprocessing
64% Login to view Permeation and Activation of the M2 Ion Channel.PDF
[248 KB]
Permeation and Activation of the M2 Ion Channel of Influenza A Virus with use of Fast Step Perfusion System
60% Login to view WR19FA 1.PDF
[220 KB]
Permeation and Activation of the M2 Ion Channel of Influenza A Virus with use of Fast Step Perfusion System
58% Login to view HS09TY Sarcoplasmic Reticulum Ca2+ Uptake and release.pdf
[1.3 MB]
Sarcoplasmic Reticulim Ca2+ Uptake and Release
56% Login to view WR04PL 1.PDF
[495 KB]
Two Distinct Ca2+ - Dependent Signaling Pathways regulate the Motor Output of Cochlear Outer Hair Cells with Pneumatic Injection System
   

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Manuals Back to Top

Displaying 1 to 2 of 2results for Coleman Superfusion Bath System  

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Description

100% Login to view metric system trivia.pdf
[146 KB]
Microsoft Word - Lesson1.doc
61% Login to view Homeothermic Blanket Systems with Flexible Probe.pdf
[185 KB]
Homeothermic Blanket System
   

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