• 16 channel data acquisition software for in vivo or in vitro respiration experiments
• For Windows® 98, ME, 2000, XP and NT
• Derives and presents online the standard parameters for respiratory studies (TV, Resp. Rate, Resistance, Conductance, Compliance)
• possibility of combination with circulatory signals (e.g. LVP, aortic pressure,aortic flow)
• In vivo:
- Bronchodilation test and bronchospasmolytic test on anesthetized animals
- Antiasthmatics test according to Konzett-Roessler (bronchial overflow measurement) or according to Einthoven (tracheal pressure measurement)
- Pulmonary air flow
- Tracheal pressure or esophageal pressure
- Arterial pressure or venous pressure
- pO2, pCO2, pH, temperature etc.
• In vitro:
- Bronchodilation test and bronchospasmolytic test on the isolated lung
- Pulmonary-vascular studies on the isolated lung
The HSE-HA PULMODYN W software can be adapted to virtually any experimental investigation in respiratory experiments. Acquisition can cover signals such as pulmonary air flow, tracheal pressure or oesophageal pressure, arterial pressure or venous pressure, pO2, pCO2, pH, temperature etc. Various parameters can be derived from these signals, e.g. tidal volume, respiration rate, peak inspiratory flow, peak expiratory flow, maximal and minimal tracheal pressure, resistance, compliance, systolic, diastolic and mean values for pressures, etc. During data acquisition all acquired signals and derived parameters can be displayed on the screen.
The HSE-PULMODYN software is available in a basic version which includes the minimal necessary algorithms for pulmonary mechanics evaluation. It can be upgraded to a more complex system including all the available algorithms. The configuration of the system is defined in configuration files to reduce the amount of settings necessary and to ensure a stable and secure system. The user has only to calibrate the signals and to fix the graphics scaling, all the hardware definitions and the algorithms used are defined in the configuration files. This reduces the amount of information necessary in the SOP’s and the possibilities of wrong settings. The configuration files can of course be changed and the software can be used in combination with a set of different configuration files to match the different experiments. PULMODYN is a menu-controlled software and employs special algorithms to calculate the standard pulmonary mechanics parameters.
The HSE-HA PULMODYN software has a maximum of 16 input channels, i.e. up to 16 different raw signals can be handled. The assignment of the signals to the individual channels is determined in the configuration files. The sample rate, the type of signals and the algorithm used for analysis are also defined in the configuration file. The arrangement of the graphic detail (raw signals) and trend (calculated parameters) is defined in the menu. The user has only to set up which of the available signals he wants to acquire and display, which of the possible parameters he wants to evaluate and display; to enter the experimental protocol and finally to calibrate before he starts the data acquisition.
The HSE-HA Data Acquisition Hardware for PULMODYN W Software is available in three versions:
• PLUGSYS Version BS4 73-0161
This version consists of the PCI A/D board DT301 and the cable for connecting to a DIM Data Interface Module installed in the PLUGSYS basic system case.
• Stand Alone Version BS4 73-0235
This version consists of the PCI A/D board DT301 and a BNC input box where signals from external amplifiers can be connected.
• Stand Alone USB Version BS4 73-3330
Hardware Requirements for Pulmodyn:
Both the PLUGSYS and Stand Alone versions require the following computer hardware:
Computer Pentium PC at least 500 MHz with one free PCI-slot,
RAM 128 MB of RAM
Operating System Windows 2000/XP or Windows NT
Hard Disk Space With at least 3.2 GB
Floppy Drive 1.44 MB
CD-ROM Drive Required
Backup Media MO drive, CD recorder or ZIP drive
Commonly Used Signals for In-Vivo Respiratory Experiments are:
• Pulmonary Air Flow
• Intrapleural Pressure
• Tracheal Pressure or Oesophageal Pressure
• Arterial Blood Pressure or Venous Blood Pressure (option)
• ECG (option)
Signals in Isolated Lung Experiments are:
• Pulmonary Air Flow
• Intrapleural Pressure
• Perfusion Pressure, venous pressure
• Perfusion Flow
• pO2, pCO2, pH
• Lung Weight
The Basic PULMODYN Calculates the Following Parameters On-Line:
From Pulmonary Air Flow RespRate, maxInspFl, maxExpFl, TV, dynResistance, Conductance, dynCompl.
From all Pulmonary Pressures Maximum, minimum, mean pressure
From Blood Pressures Systolic, diastolic, mean pressure, npmn, Heart Rate
From Perfusion Flows Maximum, minimum, mean flow, npmn
From the Pulmonary airflow Inspiratory time, Expiratory time, Apnea time, Total time
From pO2, pCO2, pH Mean value
From Temperature & Lung Weight Mean value
Note: npmn = non pulsatile mean
It is also possible to calculate specific values from these parameters by writing a formula e.g. the difference between the oesophageal and the tracheal pressure.
Additional Software Modules:
Algorithm Advanced Pulm Flow IT (inspiratory time), ET (expiratory time), AT (apnea time), TT (total time), TB (Time of brake), TP (Time of pause) Airflow at 0.5 VT
Module for Blood Pressure Systolic, diastolic, mean pressure, npmn, Heart Rate
Module for LVP LVPsys, LVPedp, dP/dtmax, dP/dtmin, heart rate
Algorithm ECG RR-I, HR
Specific parameters which are not mentioned in this list are available upon request.