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Home Ventilators Volume Controlled Inspira Advanced Safety Single Animal Volume Controlled Ventilators


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Inspira Advanced Safety Single Animal Volume Controlled Ventilators

The Inspira is the most advanced ventilator on the market and can be used for animals from mice to cats. It offers microprocessor control, easy-setup and operation, alphanumeric display, and a multitude of features including airway pressure monitoring assist mode, sigh breath, variable I:E ratio. It is available in both a pressure controlled and volume controlled model. It also features SafeRange™ a rapid setup system that uses the animal weight to calculate “average” ventilation parameters such as rate and tidal volume.
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Item Listing Full Description Specifications Journal Articles Manuals
Item# Description
557058 Inspira Advanced Safety Ventilator Volume Controlled (ASVV)
557061 Inspira Advanced Safety Ventilator Inspiratory Hold Volume Controlled (ASVV-IH)

For local pricing, contact your nearest distributor.



Full Description Back to Top

• Ventilates mice to cats with one ventilator (15 g to 10 kg)
• Easy to use
• Four models available:
— Volume-controlled (with or without Inspiratory Hold)
— Pressure-controlled (with or without Inspiratory Hold)
• Airway pressure monitoring detects over/under pressurization of lungs
• Assist Mode helps wean animal off the ventilator
• Built in sigh breath maintains optimal lung functioning
• Adjustable I:E ratio (1:4 to 4:1)
• Ability to ventilate with air or non-flammable anesthetic gases
• Quiet

Announcing our enhanced Inspira ventilator family:

• Inspira Advanced Safety Ventilator — Volume Controlled (ASVV )
• Inspira Advanced Safety Ventilator — Pressure Controlled (ASVP )
• Inspira Advanced Safety Ventilator Inspiratory Hold — Volume Controlled (ASVV-IH)
• Inspira Advanced Safety Ventilator Inspiratory Hold — Pressure Controlled (ASVP-IH)

Our Inspira ventilators are the result of extensive research and development. Each features an easy to use keypad, bright display, and all gas ports located on the front panel. Advanced functions include Airway Pressure Monitoring, Assist Mode, Programmable Sigh Breaths, and Adjustable I:E Ratio.

Call Harvard Apparatus for more details. One Ventilator — Many Animals

This is Harvard Apparatus' first ventilator that can ventilate animals from mice to cats using the same machine. It provides respiration rates from 5 to 200 bpm. The tidal volume is adjustable from 0.1 ml to 100 ml. It is no longer necessary to purchase one ventilator for mice and another for large rodents. The Inspira can do it all.

Easy to Use
Simply enter the animal's weight and press run! A microprocessor recommends the respiratory profile for a user-entered animal weight. The user may override respiratory parameters if needed. The ventilators have a bright, easy-to-read display and simple to use keypad.
All gas connections are positioned on the front of the machine for convenience. In addition to the gas ports, two analog outputs, an external trigger connector, and sync out connector are also located on the front of the machine. An RS-232 port is located on the back of the machine and can be used for remote control, data logging, or printer connection.

Airway Pressure Monitoring
Built-in pressure sensor monitors airway pressure. Under and over pressure limits are monitored. Starting limits are selected by built-in controller.

Safe Range™
Setting up the ASV ventilators is both easy and safe thanks to the Safe Range™ software. Once the animal's body weight has been entered the software computes the median settings for tidal volume and respiratory rate. These same equations are used to calculate a Safe Range™ around the median values. All the default parameter settings can be overridden. If you enter a setting outside of the Safe Range for the body mass of the animal to be ventilated you are warned that the value is outside the Safe Range™ and asked to confirm the setting.

Bright & Easy to Read Display
This new display has two lines each with 20 characters. Both the respiration rate and tidal volume are brightly displayed simultaneously.

Membrane Keypad
The new keypad is simple and intuitive. Respiration rate, tidal volume, animal weight, sigh breath, I:E ratio, and pressure limits are all accessed directly via a button on the keypad. For customized ventilation protocols, simply press the ‘SET' button and then the desired button to enter the required value on the numeric keypad. Pressing the ‘ENTER' button inputs the value.

Two RS-232 Ports
The rear of the machine has two RS-232 ports for remote control, data logging, or printer connection and also User I/O. To the side of the machine there is a window allowing the user to view piston motion.

Assist Mode
Both the volume and pressure controlled ventilators support an Assist Mode. This feature helps to wean the animal off the ventilator. When the animal attempts to initiate a breath on its own, a pressure sensor detects the drop in lung pressure. This drop initiates a ventilation cycle.

The sensitivity of the Assist Mode is adjustable from —1 to —10 cmH2O. The ventilator lets the animal initiate breaths independently as long as its breathing rate is greater than the respiration rate set by the user or calculated by the microprocessor.

Sigh Breath
With continuous, long term ventilation and the force of gravity, the animal's lungs begin to collapse. Introducing a larger than normal tidal volume over inflates the animal's lungs, periodically replicating the natural sigh. It allows the lungs to expand and opens the collapsed alveoli. The frequency of the sigh breath is user selectable and available in both the ASVV and the ASVP models.
For both ventilators, the sigh breath information is entered via the keypad. For Inspira ASVV, the user enters a sigh breath volume. With the Inspira ASVP, the user enters a sigh breath pressure. For both ventilators the sigh breath frequency may be programmed which automatically initiates sigh breaths. These breaths may also be triggered manually by pressing the SIGH button on the keypad during respiration.

Volume-Controlled vs. Pressure Controlled
The Inspira ASVV delivers the desired tidal volume to the animal by precisely controlling the stroke of the piston. Stroke speed is controlled during inspiration and expiration allowing variable inspiration-to-expiration ratios.
The Inspira ASVP delivers gas during inhalation by moving the piston while continuously monitoring the airway pressure. The microprocessor reads the increasing pressure and compares it to the maximum inspiration pressure set by the user. When the maximum pressure is reached, the piston stops. The exhale valve opens at the appropriate time determined by % inspiration time and closes when the PEEP (positive end expiratory pressure) setting is reached.

Inspiratory Hold
The newest addition to the Inspira family offers an Inspiratory Hold feature. This feature is available in both the volume and pressure controlled models. The user can enter the desired hold time and initiate the hold simply by pressing the "Inspiratory Hold" button on the keypad. Standard models can be upgraded to Inspiratory Hold models - please contact our technical support department for additional details.

PEEP - Positive End Expiratory Pressure (Inspira ASVP Only)
The Inspira ASVP also has a PEEP feature. This feature allows a positive pressure to be maintained between inspirations instead of falling to zero or near zero at the end of the expiratory phase. When the PEEP pressure is reached, the expiration valve closes until the next inspiration cycle begins. This allows the lungs to maintain a positive pressure through most or all of the breathing cycle which is a more natural state for the lungs.

Piston/Cylinder Assembly
The Inspira Ventilators use a glass and graphite piston/cylinder assembly and a microprocessor controlled actuation mechanism to precisely control respiration profiles. Two easily interchangeable piston/cylinder assemblies are available to provide 0.1 ml to 10 ml and 10 ml to 100 ml tidal volumes. Changing the piston/cylinder assembly is simple. Open the top chassis cover, unscrew the assembly, and install the new piston/cylinder assembly. The ventilator automatically detects which size cylinder is installed. Variable flow valves control the inhalation and exhalation gas flow. A window shows the piston/cylinder assembly at work inside!

Anesthetic Ventilator
Both Inspira ventilators can be used with anesthesia machines to deliver non-flammable anesthetic gases such as Nitrous Oxide, Enflurane, Sevoflurane, Halothane or Isoflurane. A future option for the Inspira ASVV and ASVP ventilators will be anesthetic agent monitoring for Nitrous Oxide, Enflurane, Sevoflurane, Halothane or Isoflurane. Please call Harvard Apparatus for more information.


Specifications Back to Top

Specifications557058557061
Number of Animals11
SpeciesMice, Rats, Guinea Pigs, Rabbits, CatsMice, Rats, Guinea Pigs, Rabbits, Cats
Weight Range Minimum15 g15 g
Weight Range Maximum10 kg10 kg
Tidal Volume Minimum0.1 ml/stroke0.1 ml/stroke
Tidal Volume Maximum100 ml/stroke100 ml/stroke
Respiration Rate Minimum5 breaths/min5 breaths/min
Respiration Rate Maximum200 breaths/min200 breaths/min
I E Ratio1:4 to 4:1 %1:4 to 4:1 %
CertificationsCECE
Port Size OD Metric1.75, 3.5, 4.1 or 5 mm adjustable1.75, 3.5, 4.1 or 5 mm adjustable
Port Size English OD1/16, 1/8, 5/32 or 3/16 in adjustable1/16, 1/8, 5/32 or 3/16 in adjustable
Control ModesVolumeVolume
Inspiratory Hold Time Full RangeNot available1 to 120 sec
Inspiratory Hold Time Safe RangeNot available1 to 60 sec
PEEPBuilt in machineBuilt in machine
Sigh PressureNot availableNot available
Inspiratory Flow0 to 12 SLPM0 to 12 SLPM
Pressure Signal0 to 5 V Analog0 to 5 V Analog
Pressure Signal Note(representing 0 to 50 cmH20)(representing 0 to 50 cmH20)
Gas SupplyRoom air or non-flammable mixed gasRoom air or non-flammable mixed gas
External Trigger+5 to +12 V peak pulse+5 to +12 V peak pulse
Resolution1 breath/min1 breath/min
Pressure Range0 to 50 cmH2O0 to 50 cmH2O
Sigh FrequencyAuto or manualAuto or manual
Respiratory AssistNot availableNot available
Signal InputsExternal triggerExternal trigger
Signal OutputSync out, 2 analog outputs (user selectable)Sync out, 2 analog outputs (user selectable)
Display2 line x 20 character VFD display2 line x 20 character VFD display
Voltage Range170 to 264 V, AC 85 to 132 V, 50/60 Hz170 to 264 V, AC 85 to 132 V, 50/60 Hz
Height Metric20.3 cm20.3 cm
Height English8.0 in8.0 in
Width Metric25.4 cm25.4 cm
Width English10.0 in10.0 in
Depth Metric43.8 cm43.8 cm
Depth English17.25 in17.25 in
Net Weight Metric9.1 kg9.1 kg
Net Weight English20 lb20 lb
ModelInspira ASVVInspira ASVV-IH

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Journal Articles Back to Top

Displaying 1 to 10 of 28results for Inspira Advanced Safety Single Animal Volume Controlled Ventilators   Page 1  2  3 

Score

Document

Description

100% Login to view VT23 Inhibition Shapes Frequency Response Areas with Small Animal Ventilator.pdf
[673 KB]
Inhibition Shapes Frequency Response Areas with Small Animal Ventilator
97% Login to view VT11 Effects of Concentrated Ambient Particles in rats and Hamsters with Small Animal Respirator.pdf
[874 KB]
Effects of Concentrated Ambient Particles in rats and Hamsters with Small Animal Respirator
86% Login to view VT35 Animal Respirator use in finding Anesthetic inhibition in ischemic and nonischemic murine heart.pdf
[194 KB]
Animal Respirator use in finding Anesthetic inhibition in ischemic and nonischemic murine heart
70% Login to view VT33 Effects of Pharyngeal Muscle Activation on Airway Size and Configuration.pdf
[146 KB]
Effects of Pharyngeal Muscle Activation on Airway Size and Configuration
68% Login to view VT13 Air-sac pressures in little penguins.pdf
[142 KB]
Air-sac pressures in little penguins
68% Login to view VT36 Ventilator use in finding Water Permeability of Capillaries in the SFO.pdf
[467 KB]
Ventilator use in finding Water Permeability of Capillaries in the SFO
68% Login to view VT31 Sickle RBC's and NOS Inhibition decrease rat cerebral blood flow.pdf
[515 KB]
Sickle RBC's and NOS Inhibition decrease rat cerebral blood flow
68% Login to view VT03 Rodent Ventilator use in finding Reduced PO2 and Adenosine Formation Preserve Arteriolar Nitric Oxide.pdf
[283 KB]
Rodent Ventilator use in finding Ventilatory and metabolic responses to hypoxia in the smallest simian primate, the pygmy marmoset
68% Login to view VT27 Critical role for CXCR2 and CXCR2 ligands during pathogenesis of ventilator-induced lung injury.pdf
[145 KB]
Depressed tolerance to fluorocarbon-simulated ischemia in failing myocardium due to impaired (Ca2+) modulation
68% Login to view VT21 Ligation of bronchial artery in sheep attenuates early pulmonary changes following exposure to smoke.pdf
[183 KB]
Rodent Ventilator use in finding arterior wall PO2 and nitric oxide release during sympathetic vasoconstriction in the rat intestine
   

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Manuals Back to Top

Displaying 1 to 1 of 1result for Inspira Advanced Safety Single Animal Volume Controlled Ventilators  

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Document

Description

100% Login to view Inspira 557058 9.pdf
[346 KB]
Harvard Inspira Advanced Safety Ventilator Manual
   

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