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Home Specialty Vertical Ussing/Diffusion Chambers


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Specialty Vertical Ussing/Diffusion Chambers

These chambers are designed in three formats for work with excised tissue segments. Tissue is affixed between the opposing faces of the half-chambers using a series of pins surrounding the opening.
Tissue diffusion chambers are constructed as two half-cells that are held together by a high tension spring retaining ring that insures leak free operation. They are available with both circular and oblong openings, depending on the tissue type under study. For example, for intestinal tissue studies, oblong openings can increase the effective surface area of the sample.

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Item# Description
660008 Specialty Vertical Chamber, Snapwell™

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Full Description Back to Top

• 14 Different chambers available in 3 configurations:
– Standard Chambers
– Low Volume Chambers
– Specialty Chambers
- Snapwell™
- Millicell®

These chambers are designed in three formats for work with excised tissue segments. Tissue is affixed between the opposing faces of the half-chambers using a series of pins surrounding the opening.
Tissue diffusion chambers are constructed as two half-cells that are held together by a high tension spring retaining ring that insures leak free operation. They are available with both circular and oblong openings, depending on the tissue type under study. For example, for intestinal tissue studies, oblong openings can increase the effective surface area of the sample.
Several low volume tissue chambers that reduce the amount of compound required to conduct permeability studies and custom chambers are also available. Up to six vertical chambers of any type can be placed in the heat block at one time, allowing convenient execution of six simultaneous transport studies under precise experimental conditions. The compact configuration, 38.1 x 10.2 x 12.7 cm (15 x 4 x 5 in), conserves valuable bench space. An optional heat block that can hold up to 24 chambers is also available. An optional adapter (perfusion cap) can be inserted into each half cell for closed perfusion applications.
Snapwell™ Diffusion Chambers
This chamber is specifically designed for use with the Snapwell™ culture insert (Corning Costar Corp.). The chamber accepts the lower section of the Snapwell, which contains the tissue culture treated membrane with cell monolayer. These Snapwell™ chambers give better results than other chambers. Their low profile reduces the unstirred water layer thus more closely approaching the real conditions in the intestine.


Specifications Back to Top

Specifications660008
660013_gr_il_150.jpg660013_gr_il_150.jpg
Exposed Tissue Area1.13 cm2
Working Reservoir Volume4 to 6 ml
Chamber TypeSnapwell™

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Journal Articles Back to Top

Displaying 1 to 8 of 8results for Specialty Vertical Ussing/Diffusion Chambers  

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Description

100% Login to view PP35 Peristaltic Pump.pdf
[381 KB]
Peristaltic pump use in finding Improvements to parallel plate flow chambers to reduce reagent and cellular requirements
70% Login to view micro eq dial2.pdf
[1.1 MB]
Control of electrostatic interactions between F-actin and genetically modified lysozyme in aqueous media
42% Login to view 96well eq dialplate2.pdf
[40 KB]
In Vitro Assessment of Plasma Protein Binding and Metabolic Stability of PTK 0796 (BAY 73-6994)
35% Login to view 96well eq dialplate4.pdf
[1.9 MB]
Kringle 5 of Human Plasminogen Induces Apoptosis of Endothelial and Tumor Cells through Surface-Expressed Glucose-Regulated Protein 78
35% Login to view dispo eq dial1.pdf
[1.4 MB]
Three-dimensional Structure of Guanylyl Cyclase Activating Protein-2, a Calcium-sensitive Modulator of Photore
35% Login to view dispo eq dial3.pdf
[868 KB]
An mRNA structure that controls gene expression by binding S-adenosylmethionine
35% Login to view 96well eq dialplate5.pdf
[317 KB]
Interspecies differences in plasma protein binding of MS-275, a novel histone deacetylase inhibitor
30% Login to view micro eq dial1.pdf
[354 KB]
Equilibrium Dialyzer for use in finding Differential ATP binding and Intrinsic ATP Hydrolysis
   

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