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Home Ventilation Sequencer Module (VSM)


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Ventilation Sequencer Module (VSM)

The HSE-HA Multiple-Channel Ventilator is a modular system for ventilation of one to eight large rodents. The respiratory rate is adjustable from 30 to 100 breaths per minute. It is based on the PLUGSYS system, see Section I for a complete description of the PLUGSYS system. The primary component is the Ventilator Sequencer Module (VSM) which plugs into a PLUGSYS mainframe case and is used to set the respiratory rate, inspiratory:expiratory (I:E) ratio and the maximum inspiratory pressure (i.e. safety pressure) for all animals.
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Item Listing Full Description Specifications Journal Articles
Item# Description
730046 Ventilator Sequencer Module (VSM)
730048 Connecting Block for up to 8 Ventilation Heads
730047 Ventilation Head Kit (includes Ventilation Head, Stand and Block Clamp)

For local pricing, contact your nearest distributor.



Full Description Back to Top

• Ventilate up to eight rodents at the same time
• Adjust tidal volume individually
• Very small dead space volume
• For applications where multiple rodents must be ventilated simultaneously (e.g. multiple blood pressure measurement)
• For Einthoven bronchospasmolysis test on multiple animals

The HSE-HA Multiple-Channel Ventilator is a modular system for ventilation of one to eight large rodents. The respiratory rate is adjustable from 30 to 100 breaths per minute. It is based on the PLUGSYS system, see Section I for a complete description of the PLUGSYS system. The primary component is the Ventilator Sequencer Module (VSM) which plugs into a PLUGSYS mainframe case and is used to set the respiratory rate, inspiratory:expiratory (I:E) ratio and the maximum inspiratory pressure (i.e. safety pressure) for all animals. The safety pressure is set by the researcher and is used to prevent over inflation of the animal’s lungs. The VSM requires a compressed air supply and, using both electronic and pneumatic controls, directs the air flow to the VSM ventilation head.
One to eight ventilation heads 73-0047 can be connected to the VSM. If more than one ventilation head is used, a connecting block 73-0048 is required. A directional valve within the ventilation head is controlled by the VSM to regulate the inspiratory and expiratory cycle. The VSM ventilation head includes all necessary tubing.
An optional MPX pressure transducer, 73-0064, can be connected to the ventilation head. This pressure transducer attached to a TAM-A transducer amplifier, 73-0065, can be used to record tracheal/airway pressures. This setup is described more thoroughly in the Einthoven Anti-asthmatics system, see our website. All components must be purchased separately.
HSE-HA Ventilation Sequencer Module (VSM)
The HSE-HA Ventilation Sequencer Module (VSM) consists of an electronic and a pneumatic section and requires a compressed air supply. The VSM module with the ventilation head operates on the principle of ‘intermittent constant flow ventilation’. A continuously adjustable air flow is passed by a main valve either to the animal (during inspiration) or to an overflow outlet (during expiration). The design of the main valve provides an adjustable, pressure controlled, protection against excessive pressure rise in the animal’s lung. The main valve is controlled electronically according to the selected respiration rate (RATE) and the selected inspiratory cycle (INSP. CYCLE %). The safety pressure which is the maximum admitted inspiratory pressure can be adjusted on the VSM module. The timing and the safety pressure are the same for all the ventilation heads, the constant air flow during inspiration can be adjusted individually on each ventilation head.


Specifications Back to Top

Specifications730046730048730047
Power Supply5 V 0.4 A and 24 V 0.18 A through connector from PLUGSYS bus system  
PLUGSYS Width*5 slot units  
Dimensions (H x W x D) Metric1128.7 x 101.6 x 220 mm  
Dimensions (H x W x D) English5.1 x 4 x 8.7 in  
ConnectorDIN 41612, 96-pin VG  
IndicationLED lights up during inspiration  
Trigger Output (BNC Socket)BNC socket on front panel (TTL open collector; inspiration = low level; expiration = high level); trigger signal also available on PLUGSYS bus system  
Compressed Air Supply: Minimum (Metric)4 bar  
Compressed Air Supply: Minimum (English)58 lbs  
Compressed Air Supply: Maximum (Metric)8 bar  
Compressed Air Supply: Maximum (English)116 lbs  
Respiratory Rate30, 40, 50, 60, 70, 80, 90, 100 breaths/min  
Inspiratory Time10, 20, 30, 40, 50, 60, 70, 80 % of total cycle duration  
Control of Ventilation Heads: Ventilation Pressure150 mmHg  
Control of Ventilation Heads: Control PressureAdjustable 0 to 50 cmH2O, safety pressure set at ‘Max. Insp. Pressure’  

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Journal Articles Back to Top

Displaying 1 to 4 of 4results for Ventilation Sequencer Module (VSM)  

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Document

Description

100% Login to view HS14 Hyperventilation and Cytokine Release.pdf
[422 KB]
Ventilator and Amplifier use in Hyperventilation Inducing release of Cytokines from Perfused Mouse Lung
41% Login to view HS13 Cardioselective KATP Channel Blockers.pdf
[165 KB]
Force Transducer use in Cardioselective KATP Channel Blockers Derived from a New Series of Anisamidoethylbenzenesulfonylthioureas
28% Login to view HS12P2 Effects of GYK!-16638 in rabbits.pdf
[236 KB]
PII: S0014-2999(00)00591-4
12% Login to view HS16 In Vivo Pharmacology of the PDE4 Inhibitor Roflumilast.pdf
[325 KB]
Transducer use In Vivo Efficacy in Airway Disease Models of Rofulmilast
   

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